Oushod Sheba

Oushod Sheba

All category

ABDORIN

OPSONIN PHARMA LTD.


TABLET
10 MG

2.01

Generic Information

Generic name

DICYCLOVERINE HYDROCHLORIDE

Indications

Dicycloverine is indicated in: Functional bowel/ irritable bowel syndrome Urinary incontinence secondary to unstable detrusor muscle Infantile colic GIT spasm Colicky abdominal pain Diverticulitis Abdominal colic

Therapeutic Class

Anticholinergics (antimuscarinics)/ Anti-spasmodics

Pharmacology

Dicycloverine HCl relieves smooth muscle spasm in the GI and urinary tract. This effect is partly due to antimuscarinic action and partly direct action on the smooth muscle.

Dosage & Administration

Oral dosage forms- Adults:10 to 20 mg three times a day. Children >6 months of age: 5 to 10 mg three times a day. Children <6 months of age: Dose must be determined by the doctor. Oral dicycloverine Hydrochloride should be started as soon as possible Intramuscular dosage form- Adults: Intramuscular injection. Not for intravenous use. The recommended intramuscular dose is 80 mg daily (in 4 equally divided doses). Intramuscular dosage form should not be used for periods longer than 1 or 2 days.

Interaction

Contradictions

Side Effects

Insomnia, mydriasis, cycloplegia, increased ocular tension, urinary hesitancy, palpitations, dyspnea.

Pregnancy & Lactation

Pregnancy: Category B. Dicycloverine was neither teratogenic nor embryocidal in animal trial. It, like other drugs should be used during pregnancy only if clearly needed. There are no data on the secretion of this drug into breast milk. Dicycloverine should be used cautiously in case of lactating mother.

Overdose Effects

Toxic reaction seldom occurs with dicycloverine. The signs and symptoms of overdosage are headache; nausea; vomiting; blurred vision; dilated pupils; hot, dry skin; dizziness; dryness of the mouth; difficulty in swallowing; and CNS stimulation.

Precaution & Warnings

Use with caution in patients with autonomic neuropathy, hepatic or renal disease, ulcerative colitis, coronary heart disease, congestive heart failure, cardiac tachyarrhythmia, known or suspected prostatic hypertrophy.

Storage Conditions

Store below 308C.